Interventional Radiotherapy (Brachytherapy) for Nasal Vestibule: Novel Strategies to Prevent Side Effects

Interventional radiotherapy (brachytherapy) has become the new therapeutic standard in management of early stages nasal vestibule tumors; fact it allows for high local control rates and low toxicity profiles. However, since more patients will receive interventional as primary treatment, is desirable to implement novel strategies reduce dose organs at risk with future aim result further lowering long-term side effects. Materials methods: We were able identify two different treatment volume, including implantation technique (the implant can be interstitial, endocavitary or mixed catheters may placed either using Paris system rules anatomical approach) distribution within most commonly used parameter consider non-uniformity ratio). subsequently propose risk, use metal shields fixed case eyes a mouth swab push away mobile organs, such mandible. algorithms verify values namely TG-43 TG-186. Results: provided an accurate literature review regarding underlining pros cons all techniques about ratio. Regarding innovative we investigated eye shielding swabs mandible by performing calculation series three consecutive patients. Our results show that reduction, both shielding, was statistically significant. Conclusion: Proper knowledge best ratio highlighted existing mandatory order volume. With regard reduction have demonstrated could play pivotal role clinical practice; fact, they are effective doses surrounding do not require any change current workflow.